Yi Fan;Pamela A. Albaugh;Gregory Chopiuk;Paul Vincent Rucker;Zhicheng Wang;Ha-Soon Choi
发明人:
Pamela A. Albaugh,Ha-Soon Choi,Gregory Chopiuk,Yi Fan,Paul Vincent Rucker,Zhicheng Wang
申请号:
US12992027
公开号:
US08507488B2
申请日:
2009.05.07
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly Ros, KDR, FMS, C-FMS, FLT3, c-Kit, JAK2, JAK3, Aurora, PDGFR, Lck, TrkA, TrkB, TrkC, IGF-IR, ALK4, ALK5 and ALK or combinations thereof.