University of Iowa Research Foundation;University of Kansas
发明人:
Ziying Yan,John F. Engelhardt,Jianming Qiu
申请号:
US15822956
公开号:
US10793835B2
申请日:
2017.11.27
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The invention provides an isolated chimeric virus comprising bocavirus capsid protein and a recombinant adeno-associated viral (AAV) genome, an isolated rBoV comprising human bocavirus capsid protein and a recombinant BoV genome, and uses therefor. For example, the chimeric virus may be employed to deliver transgenes, such as those encoding therapeutic or prophylactic gene products, to mammalian cells.