PASSINI MARCO,CHENG SENG,DODGE JAMES,SHIHABUDDIN LAMYA,ORIORDAN CATHERINE R
申请号：
IN4196/KOLNP/2007
公开号：
IN264058B
申请日:
2007.11.01
申请国别(地区):
IN
年份:
2014
代理人:
摘要：
This disclosure provides methods and compositions for treating disorders or injuries that affect motor function and control in a subject. In one aspect, the invention provides a method to deliver a transgene to a subjects spinal cord by administering a recombinant neurotropic viral vector containing the transgene. The viral vector delivers the transgene to a region of the deep cerebellar nuclei region of the brain. Also provided are compositions and methods to deliver a transgene to a subjects spinal cord by administering a recombinant neurotropic viral vector containing the transgene to the motor cortex region of the subjects brain.
