Lindsay Wray,Jelena Rnjak-Kovacina,David L. Kaplan
申请号：
US14356958
公开号：
US20140370094A1
申请日:
2012.11.08
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The inventions provided herein relate to silk-based scaffolds and methods of producing the same, which can be used for a range of tissue engineering applications. The fabrication methods described herein provide a versatile platform to incorporate hollow conduits (e.g., for nutrient/oxygen delivery) through three-dimensional silk-based scaffolds that have tunable bulk properties (e.g., but not limited to, porosity, mechanical, degradation rate) and allow endothelialization and/or cell compartmentalization, for engineering a variety of complex tissue equivalents.
