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Microneedle device having a peptide therapeutic agent and an amino acid, methods of making and using the same
专利权人:
3M Innovative Properties Company
发明人:
Zhang, Ying,Fenn, Percy T.,Johnson, Peter R.
申请号:
AU2012345768
公开号:
AU2012345768A1
申请日:
2012.11.30
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
A medical device including an array of microneedles and a coating disposed on or within the microneedles and a method of making such a device are disclosed. The coating includes a peptide therapeutic agent and an amino acid. A method of stabilizing a peptide therapeutic agent with an amino acid on an array of microneedles is also disclosed. In some cases, the peptide therapeutic agent and the amino acid either both have a net positive charge or both have a net negative charge. In some cases, the peptide therapeutic agent is histidine.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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