UNIVERSITE PARIS-SUD;INSERM(INSTITUT NATIONA DE LA SANTE ET DE LA RECHERCHE MEDICALE
发明人:
Olivier CHRISTOPHE,Cecile DENIS,Peter LENTING
申请号:
US15746970
公开号:
US20180334662A1
申请日:
2016.07.26
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to mutated factor (FX) polypeptides and uses thereof for the treatment of haemophilia. In particular, the present invention relates to a mutated factor X (FX) polypeptide which comprises a heavy chain wherein at least one amino acid residue at position 401 or 408 is mutated.