LEE CHANGSIK,LEE JAEKWANG,SONG HYESEUNG,BAE DAEKWON,HA NINA,KIM IL HYANG
申请号：
IN201717036779
公开号：
IN201717036779A
申请日:
2017.10.17
申请国别(地区):
IN
年份:
2017
代理人:
摘要：
The present invention relates to novel heterocyclicalkyl derivatives having histone deacetylase (HDAC) inhibitory activity optical isomers thereof or pharmaceutically acceptable salts thereof the use thereof for the preparation of medicaments pharmaceutical compositions containing the same a method for treating diseases using the composition and methods for preparing the novel heterocyclicalkyl derivatives. The novel heterocyclicalkyl derivatives according to the present invention are selective histone deacetylase (HDAC) inhibitors and may be effectively used for the treatment of histone deacetylase mediated diseases such as cell proliferative diseases inflammatory diseases autosomal dominant diseases genetic metabolic diseases autoimmune diseases acute/chronic neurological disease hypertrophy heart failure ocular diseases or neurodegenerative diseases.
