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Heterodimers and purification thereof
专利权人:
Philip C Jones;University of Natural Resources and Life Sciences
发明人:
Philip C Jones,Gerhard Stadlmayr
申请号:
GB201814284
公开号:
GB2563531A
申请日:
2017.02.02
申请国别(地区):
GB
年份:
2018
代理人:
摘要:
A protein comprising a human IgG Fc variant fragment monomer, capable of binding superantigen protein A, but not superantigen protein G [pA+/pG-] comprising serine at position (428), serine at position (434) and optionally histidine at position (436), with reference to human IgG1 or comprising these residues at the corresponding positions in human IgG 2, 3, or 4 as shown in the alignment in Figure 24, wherein positions are defined according to the EU index of Kabat.
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