HAVENSTRITE, KAREN,MCCRAY, VICTOR W.,FELKINS, BRANDON M.,COOK, PAUL
申请号：
CA2970010
公开号：
CA2970010A1
申请日:
2015.12.09
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
Medical devices with a hydrogel layer covalently attached to a portion of the outer surface of the medical device are provided along with methods for applying the coating. The hydrogel layer can include a first polymer species comprising polyethylene glycol (PEG) and a second polymer species. Examples of the second polymer species include PEG and polyacrylamide (PAM). The first and second species can be at least partially cross-linked. Methods for forming the hydrogel coatings on the medical devices are provided including nucleophilic conjugate reactions, such as Click reactions.
