HAVENSTRITE, Karen,MCCRAY, Victor W.,FELKINS, Brandon M.,COOK, Paul
申请号:
EP15867618
公开号:
EP3229851A4
申请日:
2015.12.09
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
Medical devices with a hydrogel layer covalently attached to a portion of the outer surface of the medical device are provided along with methods for applying the coating. The hydrogel layer can include a first polymer species comprising polyethylene glycol (PEG) and a second polymer species. Examples of the second polymer species include PEG and polyacrylamide (PAM). The first and second species can be at least partially cross-linked. Methods for forming the hydrogel coatings on the medical devices are provided including nucleophilic conjugate reactions, such as Click reactions.