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NOVEL ANILINE DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF
专利权人:
Kissei Pharmaceutical Co.; Ltd.
发明人:
INOUE, Hitoshi,OHNO, Kohsuke,NAKAMURA, Tetsuya,OHSAWA, Yusuke
申请号:
EP15755976
公开号:
EP3112347A4
申请日:
2015.02.27
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
[Problem] The present invention provides a novel compound having an S1P 1 receptor antagonistic activity. [Solution] The present invention provides a compound represented by the general formula (I): (in the formula, R 1 , R 2 and R 3 are each a hydrogen atom, a halogen atom, a C 1-6 alkyl group, a halo C 1-6 alkyl group or the like, R 4 is a C 1-6 alkyl group or the like, R 5 is a C 1-6 alkyl group or the like, R 6 is a C 1-6 alkyl group or the like, R 7 is a hydrogen atom, a halogen atom, a C 1-6 alkyl group or the like, R 8 is a halogen atom, a C 1-6 alkyl group, a halo C 1-6 alkyl group, a C 1-6 alkoxy group or the like, and R 9 is a hydrogen atom or a C 1-6 alkyl group.) or a pharmaceutically acceptable salt thereof, a pharmaceutical compositions containing same, and use thereof. The compounds of the present invention have an excellent SIP 1 receptor antagonistic activitiy and therefore are useful as an agent for the treatment or prevention of antoimmune diseases and the like.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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