PROBLEM TO BE SOLVED: To provide a method of manufacturing a sheet, the sheet allowing a liquid medicine being filled into needle-like recessed portions without pressing the liquid medicine or opening through-holes in a mold to suck the liquid medicine and the sheet eliminating curling up of the mold.SOLUTION: A nozzle 34 includes a discharge port 42 upstream of a lip surface 32 of the nozzle for discharging a liquid medicine 22 and a suction port 43 downstream of the lip surface for sucking the air in needle-like recessed portions 15, the nozzle also comprising a suction port/atmosphere communication structure 44 for communicating the suction port 43 and atmosphere with the nozzle 34 pressed against a surface of a mold 13. In a liquid medicine filling step, the air in the needle-like recessed portions 15 is sucked by moving the nozzle 34 so as to position the suction port 43 on the needle-like portions 15 and then the liquid medicine 22 is filled into the needle-like recessed portions 15 by communicating the needle-like recessed portions 15 with the discharge port 42.SELECTED DRAWING: Figure 12ACOPYRIGHT: (C)2017,JPO&INPIT【課題】薬液を加圧したり、モールドに貫通孔を開けて吸引したりすることなくして薬液を針状凹部に充填でき、且つモールドの捲れ上がりのないシートの製造方法を提供する。【解決手段】ノズル34のリップ面32の上流側に薬液22を吐出する吐出口42を設け、下流側に針状凹部15内の空気を吸引する吸引口43を設け、ノズル34をモールド13表面に押し付けた状態で吸引口43と大気とを連通する吸引口大気連通構造44を有し、薬液充填工程では、吸引口43が針状凹部15上に位置するようにノズル34を移動させて針状凹部15内の空気を吸引し、針状凹部15と吐出口42とを連通させることにより、薬液22を針状凹部15内に充填する工程と、を順に行う。【選択図】図12A
