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PEPTIDES INHIBITEURS DE L'EXOCYTOSE NEURONALE
专利权人:
LIPOTEC S.A.
发明人:
CARRENO SERRAIMA, CHRISTINA,PONSATI OBIOLS, BERTA,VAN DEN NEST, WIM,FERNANDEZ CARNEADO, JIMENA,FERRER MONTIEL, ANTONIO,CEBRIAN PUCHE, JOAN,ALMINANA DOMENECH, NURIA
申请号:
CA2666516
公开号:
CA2666516C
申请日:
2007.10.24
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The invention relates to peptides having general formula R1-AA-R2, which can regulate neuronal exocytosis, the stereoisomers of said peptides, racemic or non-racemic mixtures thereof and the cosmetically or pharmaceutically acceptable salts of same, in which: AA is a sequence with 3 - 40 adjacent amino acids, contained in the amino acid sequence of protein SNAP-25; R1 is selected from the group formed by H or alkyl, aryl, aralkyl or acyl group; and R2 is selected from the group formed by amino, hydroxyl and thiol which may or may not be substituted with cyclic or aliphatic groups, on the condition that when R1 is H or acetyl, R2 is not unsubstituted amino, hydroxyl or thiol. The invention also relates to a method for obtaining cosmetic or pharmaceutical compositions containing same and to the use thereof to treat conditions requiring regulation of neuronal exocytosis, preferably to treat the skin.
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