A mouthpiece for a handheld inhaler is disclosed. A housing of the mouthpiece includes an inlet, an outlet opening, and a channel extending through the housing connecting the inlet and the outlet opening for directing an aerosol from the inlet to the outlet opening. An anterior portion of the housing (4) is configured for placement in the mouth of a patient. The anterior portion of the housing is configured to direct the outlet opening upwardly in the patients oral cavity when in the mouth of the patient. Other embodiments include an outlet opening placed closer to the upper side of the housing than to the lower side of the housing. Further, an inhaler having a mouthpiece is disclosed