A surgical staple includes a backspan and a pair of deformable legs extendingfromthe backspan and terminating in a penetrating end. The backspan and deformablelegs areformed from a wire having a curvilinear cross-section defining a major axisand a minor axiswith a portion of the wire above the major axis defining a first curvedsurface and a portion ofthe wire below the major axis defining a second curved surface, and a portionof the wire tothe left of the minor axis defining a third curved surface and a portion tothe right of theminor axis defining a fourth curved surface being different than the first,second, and thirdcurved surfaces. One or more of the curved surfaces is different than theremaining curvedsurfaces.