PANITCH, ALYSSA,PADERI, JOHN, ERIC,PARK, KINAM,STUART, KATHERINE,HIGBEE, STEVE
申请号:
EP09725336
公开号:
EP2280720A4
申请日:
2009.03.27
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
This invention relates to collagen-binding synthetic peptidoglycans and engineered collagen matrices comprising a collagen matrix and a collagen-binding synthetic peptidoglycan where the collagen-binding synthetic peptidoglycan can be aberrant or can have amino acid homology with a portion of the amino acid sequence of a protein or a proteoglycan that regulates collagen fibrillogenesis. The invention also relates to kits, compounds, compositions, and engineered graft constructs comprising such collagen-binding synthetic peptidoglycans or engineered collagen matrices and methods for their preparation and use.