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COLLAGEN-BINDING SYNTHETIC PEPTIDOGLYCANS, PREPARATION, AND METHODS OF USE
专利权人:
Purdue Research Foundation
发明人:
Alyssa Panitch,John Eric Paderi,Kinam Park,Katherine Allison Stuart,Steve Higbee
申请号:
US15369489
公开号:
US20170275345A1
申请日:
2016.12.05
申请国别(地区):
US
年份:
2017
代理人:
摘要:
This invention relates to collagen-binding synthetic peptidoglycans and engineered collagen matrices comprising a collagen matrix and a collagen-binding synthetic peptidoglycan where the collagen-binding synthetic peptidoglycan can be aberrant or can have amino acid homology with a portion of the amino acid sequence of a protein or a proteoglycan that regulates collagen fibrillogenesis. The invention also relates to kits, compounds, compositions, and engineered graft constructs comprising such collagen-binding synthetic peptidoglycans or engineered collagen matrices and methods for their preparation and use.
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