An antioxidant-promoting composition that increase antioxidant defensepotential in a subject is disclosed comprising Bacopa monniera extract; milkthistle extract, ashwagandha powder, green tea extract, Gotu kola powder,Ginko biloba leaf extract; Aloe vera powder; turmeric extract; and N-acetylcysteine. The antioxidant-promoting composition of the invention safetyinduces cellular antioxydant potential to achieve an averhall net decrease inoxidative stress without the undesirable side-effects associated with theindividual components of the antioxidant-promoting composition. Also disclosedis a method for reducing the undesirable side-effects of free radicals in asubject by administering to a subject in need of such antioxidants aneffective amount of antioxidant-promoting composition of the invention.