CHUNG CHAN;HONG Y. LIU;DENNIS L. DONG;PAUL O. SHEPPARD;KEVIN M. KLUCHER;THOMAS R. BUKOWSKI;LOWELL J. BRADY
发明人:
LOWELL J. BRADY,KEVIN M. KLUCHER,CHUNG CHAN,DENNIS L. DONG,HONG Y. LIU,PAUL O. SHEPPARD,THOMAS R. BUKOWSKI
申请号：
US13161720
公开号：
US20120004161A1
申请日:
2011.06.16
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Homogeneous preparations of IL-28A, IL-28B, and IL-29 have been produced by mutating one or more of the cysteine residues in the polynucleotide sequences encoding the mature proteins. The cysteine mutant proteins can be shown to either bind to their cognate receptor or exhibit biological activity. One type of biological activity that is shown is an antiviral activity.
