BRADY, LOWELL J.,KLUCHER, KEVIN M.,CHAN, CHUNG,DONG, DENNIS L.,LIU, HONG Y.,SHEPPARD, PAUL O.,BUKOWSKI, THOMAS R.
申请号：
CA2534907
公开号：
CA2534907C
申请日:
2004.08.09
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
Homogeneous preparations of IL-28A, IL-28B, and IL-29 have been produced bymutating one or more of the cysteine residues in the polynucleotide sequencesencoding the mature proteins. The cysteine mutant proteins can be shown toeither bind to their cognate receptor or exhibit biological activity. One typeof biological activity that is shown is an antiviral activity.
