Provided herein are methdos of treating a disease, disorder, or condition, mediated at least in part by the adenosine A2Areceptor (A2AR) and/or the adenosine A2Breceptor (A2BR) using Compound I:(Compound I).In some embodiments, the disease or disorder is a cancer related disorder. Also provided herein are pharmaceutical compositions and single unit dosages of of Compound I.本文中提供使用化合物I來治療至少部分由腺苷A2A受體(A2AR)及/或腺苷A2B受體(A2BR)介導之疾病、病症或病狀的方法:(化合物I)。在一些實施例中,該疾病或病症為癌症相關病症。本文中亦提供化合物I之醫藥組合物及單一單位劑量。