用於治療癌症相關病症之唑并嘧啶农业专利-农业学术服务平台

发明人:: BEATTY, JOEL,比提　乔伊尔,比提　喬伊爾,DEBIEN, LAURENT,戴宾　劳伦特,戴賓　勞倫特,JEFFREY, JENNA,杰佛瑞　珍那,傑佛瑞　珍那,LELETI, MANMOHAN REDDY,赖勒提　曼摩汉　瑞迪,賴勒提　曼摩漢　瑞迪,MANDAL, DEBASHIS,曼多　廸巴西斯,MILES, DILLON,迈尔斯　迪伦,邁爾斯　迪倫,POWERS,,比提乔伊尔,比提喬伊爾,戴宾劳伦特,戴賓勞倫特,杰佛瑞珍那,傑佛瑞珍那,赖勒提曼摩汉瑞迪,賴勒提曼摩漢瑞迪,曼多廸巴西斯,迈尔斯迪伦,邁爾斯迪倫

摘要：: Compound that is an inhibitor of at least one of the A2Aand A2Badenosine receptors, and compositions containing the compound and methods for synthesizing the compound, are described herein. The use of such compound and compositions for the treatment of a diverse array of diseases, disorders, and conditions, including cancer- and immune-related disorders that are mediated, at least in part, by the adenosine A2Areceptor and/or the adenosine A2Breceptor.本文闡述作為A2A及A2B腺苷受體中之至少一者之抑制劑的化合物及含有該化合物之組合物及合成該化合物之方法。本文闡述該化合物及該等組合物之用途，其可用於治療各種各樣的疾病、病症及病況，包括至少部分地由該腺苷A2A受體及/或該腺苷A2B受體介導之癌症相關及免疫相關病症。