CARVEN, GREGORY, JOHN,VAN EENENNAAM, HANS,DULOS, GRADUS, JOHANNES
申请号:
PH12015501524
公开号:
PH12015501524A1
申请日:
2015.07.06
申请国别(地区):
PH
年份:
2016
代理人:
摘要:
Antibodies which block the binding of human Programmed Death Receptor l(hPD-l) to its ligands (hPD-Ll or hPD-L2) and their variable region sequences are disclosed. A method of increasing the activity (or reducing downmodulation) of an immune response through the PD-I pathway is also disclosed.