ANTIBODIES TO HUMAN PROGRAMMED DEATH RECEPTOR PD-1

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专利权人:

MERCK SHARP & DOHME B.V.

发明人:

GREGORY JOHN CARVEN,HANS VAN EENENNAAM,GRADUS JOHANNES DULOS

申请号：

PT08768485

公开号：

PT2170959E

申请日:

2008.06.13

申请国别(地区):

PT

年份:

2014

代理人:

摘要：

Antibodies which block the binding of human Programmed Death Receptor 1 (hPD-1) to its ligands (hPD-L1 or hPD-L2) and their variable region sequences are disclosed. A method of increasing the activity (or reducing downmodulation) of an immune response through the PD-1 pathway is also disclosed.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/