A medication packaging device includes a frame structure on which a guide unit is removably fastened, the guide unit having multiple receptacle openings and a dispensing opening. The device also includes multiple storage and dispensing stations, each having a storage housing and a dispensing station having a medication dispensing channel, as well as a holding unit having a plurality of mounts. For each mount, a medication slide and a storage and dispensing station are arranged such that the receptacle openings of the medication slides are associated with the medication dispensing channels of the dispensing stations and the dispensing openings of the medication slides are associated with the receptacle openings of the guide unit. The holding unit and the frame structure are fastened on or in the device to be movable relative to one another so that the guide unit is accessible from outside the device when in an access position.