UTILISATION DE CXCL12 POUR FAVORISER LA SURVIE, LA FONCTION ET L'IMMUNOISOLEMENT DE CELLULES BÊTA DÉRIVÉES DE CELLULES SOUCHES

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专利权人:

The General Hospital Corporation

发明人:

申请号：

EP18857678.9

公开号：

EP3684385A2

申请日:

2018.09.20

申请国别(地区):

EP

年份:

2020

代理人:

摘要：

The present invention relates to compositions comprising at least one in vitro-developed β-cell and a CXCL12 polypeptide encapsulated in a microcapsule. The invention further relates to methods for treating diabetes, accelerating the normalization of hyperglycemia, and preventing fibrotic pericapsular overgrowth of microcapsules using transplanted human stem cell-derived β cells co-encapsulated with a CXCL12 polypeptide.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/