Prafulkumar Tulshibhai Chovatia,Martin Clive Hutchings,Boris Kroeplien,James Thomas Reuberson
申请号:
US15580054
公开号:
US20180222868A1
申请日:
2016.06.07
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A series of substituted indazole derivatives, being potent modulators of human TNFa activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.