The disclosed subject matter is directed to volume expanders for use with endoscopes, particularly concerning low-pressure applications, such as sterilization. A volume expander may include an enclosure having a port and a wall including an outer surface and an inner surface, and a vent cap disposed proximate the port. The port may be a single port to which the vent cap is affixed. The volume expander permits gas within recesses of an endoscope to expand, but provides a barrier between the recesses of the endoscope and the surrounding environment.
