Disclosed is an inflatable mattress containing a plurality of air or fluid cells combined into zones, inflated through a valve with multiple ports to allow faster and easier inflation. The inflatable mattress or cushion has a base and an array of upstanding fluid filled cells on one side of the base, the array of cells being divided into a plurality of inflation zones, each inflation zone having a fluid conduit that connects the inflation zone and a valve. A valve is attached to the mattress or cushion and operates to place the plurality of inflation zones into or out of fluid communication with each other. A conduit connector slides or rotates within the valve to isolate the zones with a tight seal to retain the fluid in the zones, or connect the inflation zones to allow inflation or deflation.