Axel Visel,John L. R. Rubenstein,Ying-Jiun (Jasmine) Chen,Len A. Pennacchio,Daniel Vogt,Cory Nicholas,Arnold Kriegstein
申请号：
US14512306
公开号：
US09952216B2
申请日:
2014.10.10
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Herein are described a set of novel specific human enhancers for specific forebrain cell types used to study and select for human neural progenitor cells. This approach enables the ability to generate interneurons from human ES, iPS and iN cells, making them available for human transplantation and for molecular/cellular analyzes. These approaches are also directly applicable to generating other neuronal cell types, such as cortical and striatal projection neurons, which have implications for many human diseases.
