DEJONGE, BOUDEWIJN LODEWIJK MARIA,DURAND-REVILLE, THOMAS FRANCOIS,VERHEIJEN, JEROEN CUNERA,TOMMASI, RUBEN,MUELLER, JOHN
申请号:
CA2966632
公开号:
CA2966632A1
申请日:
2015.11.17
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The present invention is directed to combinations of a ß-lactamase inhibitor with sulbactam and, optionally, imipenem/cilastatin. The combinations are useful for the treatment of bacterial infections, including infections caused by drug resistant organisms, including multi-drug resistant pathogens. More particularly, the invention relates to a combination of ß-lactamase inhibitor compound 1 : or a pharmaceutically acceptable salt thereof, with sulbactam, or a pharmaceutically acceptable salt thereof, and, optionally, imipenem/cilastatin, or a pharmaceutically acceptable salt thereof.