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Tricyclic compounds as inhibitors of immunosuppression mediated by tryptophan metabolization
专利权人:
Newlink Genetics Corporation
发明人:
Kumar, Sanjeev,Waldo, Jesse,Jaipuri, Firoz,Mautino, Mario
申请号:
AU2014241079
公开号:
AU2014241079B2
申请日:
2014.03.10
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
Presently provided are inhibitors of IDO and TDO and pharmaceutical compositions thereof, useful for modulating an activity of indoleamine 2,3-dioxygenase and tryptophan 2,3 dioxygenase; treating immunosuppression; treating a medical conditions that benefit from the inhibition of tryptophan degradation; enhancing the effectiveness of an anti-cancer treatment comprising administering an anti-cancer agent; treating tumor-specific immunosuppression associated with cancer; and treating immunosupression associated with an infectious disease.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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