CHESTER CHENGUANG YUAN,DANIEL B. HORNE,DAVID J. ST. JEAN JR.,HOLGER MONENSCHEIN,JAMES BROWN,JIAN J. CHEN,KAUSTAV BISWAS,MATTHEW R. KALLER,QINGYIAN LIU,SCOTT HARRIED,THOMAS T. NGUYEN,VIJAY KESHAV GORE
申请号：
BR112013033316
公开号：
BR112013033316A2
申请日:
2012.06.21
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
Compounds of Formula I are useful as antagonists of TRPM8. Such compounds are useful in treating a number of TRPM8 mediated disorders and conditions and may be used to prepare medicaments and pharmaceutical compositions useful for treating such disorders and conditions. Examples of such disorders include, but are not limited to, migraines and neuropathic pain. Compounds of Formula I have the following structure: where the definitions of the variables are provided herein.
