A pressure support system configured to deliver a pressurized flow of breathable gas to the airway of a subject is described. The system is configured to treat obstructive sleep apnea, other sleep disordered breathing, and/or other respiratory issues with limited flow respiration therapy, and/or other therapies. Limited flow respiration therapy may be an alternative to CPAP, for example. The system is configured to limit flow rate compensation, pressure compensation, and/generator or compensation of other parameters during inspiration to values proportional to the current leak to achieve limited flow respiration therapy. In some embodiments, the system comprises one or more of a pressure generator, a subject interface, one or more sensors, a processor, a user interface, electronic storage, and/or other components.
