THE PROCTER & GAMBLE COMPANY;THE CLEVELAND CLINIC FOUNDATION
发明人:
HAZEN, STANLEY LEON,GARCIA-GARCIA, JOSE CARLOS,GERBERICK, GEORGE FRANKLIN,WOS, JOHN AUGUST,STANTON, DAVID THOMAS,INGLIN, THOMAS ALFRED,REILLY, MICHAEL,DEUTSCH, ANGELA JANE,REED, JODIE MICHELLE,CODY, D
申请号:
CA3007081
公开号:
CA3007081A1
申请日:
2016.12.01
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The invention provides one or more methods of inhibiting the conversion of choline to trimethylamine (TMA) and lowering TMAO in an individual comprising administering to the individual one or more compositions comprising a compound set forth in Formula (I) wherein the compound is administered in an amount effective to inhibit formation of trimethylamine (TMA) from choline in the individual.