Stanley Leon HAZEN,Jose Carlos GARCIA-GARCIA,George Franklin GERBERICK,John August WOS,David Thomas STANTON,Thomas Alfred INGLIN,Michael REILLY,Angela Jane DEUTSCH,Jodie Michele REED,David Blair CODY
申请号:
US15366819
公开号:
US20170151208A1
申请日:
2016.12.01
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The invention provides one or more methods of inhibiting the conversion of choline to trimethylamine (TMA) and lowering TMAO in an individual comprising administering to the individual one or more compositions comprising a compound set forth in Formula (I):wherein the compound is administered in an amount effective to inhibit formation of trimethylamine (TMA) from choline in the individual.