ANALOGUES DE 6-ALKYL-N-(PYRIDIN-2-YL)-4-ARYLOXYPICOLINAMIDE EN TANT QUE MODULATEURS ALLOSTÉRIQUES NÉGATIFS DE MGLUR5 ET PROCÉDÉ POUR LES PRÉPARER ET LES UTILISER

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专利权人:

VANDERBILT UNIVERSITY

发明人:

CONN, P., JEFFREY,LINDSLEY, CRAIG, W.,EMMITTE, KYLE, A.,RODRIGUEZ, ALICE, L.,FELTS, ANDREW, S.,JONES, CARRIE, K.,BATES, BRITTNEY, S.,CHAUDER, BRIAN, A.

申请号：

EP12752374

公开号：

EP2680849A4

申请日:

2012.03.05

申请国别(地区):

EP

年份:

2015

代理人:

摘要：

Disclosed are negative allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5)； synthetic methods for making the compounds； pharmaceutical compositions comprising the compounds； and methods of treating neurological and psychiatric disorders associated with glutamate dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

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中国工程科技知识中心

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http://www.ckcest.cn/home/