ANALOGUES DE 6-ALKYL-N-(PYRIDIN-2-YL)-4-ARYLOXYPICOLINAMIDE EN TANT QUE MODULATEURS ALLOSTERIQUES NEGATIFS DE MGLUR5 ET PROCEDE POUR LES PREPARER ET LES UTILISER
CONN, P. JEFFREY,LINDSLEY, CRAIG W.,EMMITTE, KYLE A.,RODRIGUEZ, ALICE L.,FELTS, ANDREW S.,JONES, CARRIE K.,BATES, BRITTNEY S.,CHAUDER, BRIAN A.
申请号：
CA2828877
公开号：
CA2828877A1
申请日:
2012.03.05
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
Disclosed are negative allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5)； synthetic methods for making the compounds； pharmaceutical compositions comprising the compounds； and methods of treating neurological and psychiatric disorders associated with glutamate dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
