METHODS OF TREATING ELEVATIONS IN MTOR SIGNALING

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专利权人:

Mark F. Bear

发明人:

Mark F. Bear,Benjamin David Auerbach

申请号：

US13455679

公开号：

US20120264784A1

申请日:

2012.04.25

申请国别(地区):

US

年份:

2012

代理人:

摘要：

Subjects having elevated signaling of a mammalian target of rapamycin (mTOR) are treated with compositions that include at least one compound that activates a Group 1 mGluR. In an embodiment, the subject has tuberous sclerosis complex (TSC). In an embodiment, the compound is a Group 1 mGluR agonist. In another embodiment, the compound is a Group 1 mGluR positive allosteric modulator.

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