FRAUNHOFER-GESELLSCHAFT ZUR FÖERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
发明人:
Klaus SCHOLICH,Gerd GEISSLINGER,Natasja DE BRUIN,Sebastian ZINN
申请号：
US15509639
公开号：
US20170281575A1
申请日:
2015.10.22
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention pertains to novel analgesics useful for treating pain. BLT2 agonists were found to desensitize TRPV1 mediated signaling in sensory neurons. Thus the invention provides BLT2 agonists as novel pain therapeutics. Additional aspects of the invention pertain to combinations of BLT2 agonists with BLT1 antagonists for treating pain in subjects. Pharmaceutical compositions and kits comprising the new analgesics of the invention are furthermore provided.
