An imaging system includes a primary probe that includes a substrate； an ultrasound transducer disposed in the substrate to irradiate a first tissue with an ultrasound frequency； a first near infrared source to irradiate the first tissue with a first near infrared wavelength； and a first light detector to detect a first detected wavelength from the first tissue； an auxiliary probe that includes a second near infrared source configured to irradiate a second tissue with a second near infrared wavelength； and a second light detector configured to detect a second detected wavelength from the second tissue. The system also can include an optical tomography device； an ultrasound device； and a processor unit. A process for imaging includes disposing the primary probe on a first tissue, disposing an auxiliary probe on a second tissue, irradiating the first tissue, and irradiating the second tissue to produce an image of the first tissue.
