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CYCLIC CARBOXAMIDE COMPOUNDS AND ANALOGUES THEREOF AS OF HEPATITIS C VIRUS
专利权人:
ACHILLION PHARMACEUTICALS; INC
发明人:
ZHANG, SUOMING,PHADKE, AVINASH,DESHPANDE, MILIND,GADHACHANDA, VENKAT
申请号:
NZ59211009
公开号:
NZ592110A
申请日:
2009.11.20
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed are compounds of formula I, or a pharmaceutically acceptable salt thereof, wherein the substituents are as described within the specification. An example of a compound of formula I includes (2R,6S,16aS,Z)-6-tert-butyl-N-(cyclopropylsulfonyl)-2-(7-methoxy-2-phentlquinolin-4-yloxy)-5,8,16-trioxo-1,2,3,5,6,7,8,9,10,11,13a,14,14a,15,16,16a-hexadecehydrocyclopropa[n]pyrrolo[2,1-c][1,4,7]triazacyclopentadecine-14a-carboxamide. Further disclosed is a pharmaceutical composition comprising a therapeutically effective amount of a compound or salt of formula I, and the use of a compound or salt of formula I in the manufacture of a medicament for the treatment of a Hepatitis C infection in a patient.
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