Andrew Lennard LEWIS;Peter William STRATFORD;Maria Victoria GONZALEZ.FAJARDO;Yiqing TANG
发明人:
Andrew Lennard LEWIS,Peter William STRATFORD,Maria Victoria GONZALEZ.FAJARDO,Yiqing TANG
申请号：
US13452493
公开号：
US20120201867A1
申请日:
2012.04.20
申请国别(地区):
US
年份:
2012
代理人:
摘要：
An embolic composition comprises microspheres formed of water-insoluble water-swellable anionic polymer having swollen diameter more than 100 μm, and a cationic camptothecin compound, preferably irinotecan. The microspheres are preferably formed of crosslinked polyvinylalcohol, preferably of ethylenically unsaturated polyvinylalcohol macromer, crosslinked with anionic ethylenically unsaturated anionic comonomer. The compositions are used to treat hypervascular tumours for instance colorectal metastases of the liver.
