LEWIS, ANDREW, LENNARD,STRATFORD, PETER, WILLIAM,GONZALEZ-FAJARDO, MARIA VICTORIA,TANG, YIQING
申请号:
HK14112213.0
公开号:
HK1198691A
申请日:
2014.12.04
申请国别(地区):
HK
年份:
2015
代理人:
摘要:
An embolic composition comprises microspheres formed of water-insoluble water-swellable anionic polymer having swollen diameter more than 100[mu]m, and a cationic camptothecin compound, preferably irinotecan. The microspheres are preferably formed of crosslinked polyvinylalcohol, preferably of ethylenically unsaturated polyvinylalcohol macromer, crosslinked with anionic ethylenically unsaturated anionic comonomer. The compositions are used to treat hypervascular tumours for instance colorectal metastases of the liver.