LOENN, Hans,CONNOLLY, Stephen,SWALLOW, Steven,KARLSSON, Staffan PO,AURELL, Carl-Johan,PONTEN, John Fritiof,DOYLE, Kevin,VAN DE POËL, Amanda,JONES, Graham,WATSON, David,MACRITCHIE, Jaqueline,PALMER, Ni
申请号:
HUE15701577
公开号:
HUE038274T2
申请日:
2015.01.23
申请国别(地区):
HU
年份:
2018
代理人:
摘要:
The present disclosure relates to certain (2 S )- N -[(1 S )-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamide compounds (including pharmaceutically acceptable salts thereof), that inhibit dipeptidyl peptidase 1 (DPP1) activity, to their utility in treating and/or preventing clinical conditions including respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), to their use in therapy, to pharmaceutical compositions containing them and to processes for preparing such compounds.