The invention concerns a method of sterilization and/or inactivation of at least one surface of at least one contaminated object. The method being characterized in that one subjects the surface to the discharge plasma generated from an applicator of electromagnetic field of linear type, the plasma having a temperature and an absorbed power per unit of volume predetermined by the operating conditions, so as to sterilize the surface without significantly degrading it. The invention also concerns a device enabling the sterilization and/or inactivation of at least one surface of at least one contaminated object by means of a plasma. This method and this device can be used to sterilize or inactivate several types of objects, such as packages, films, metal plates, dielectric plates, prosthesis used in the medical field, etc.