ZAHN, STEFAN,ZEUTHEN, LOUISE HJERRILD,HANSEN, ANKER JON,KJÆRGAARD, KRISTIAN,LUND, SOREN
申请号:
CA2838497
公开号:
CA2838497A1
申请日:
2012.06.04
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The present invention concerns human antibodies recognising the human C5a receptor. By binding to C5aR the antibodies inhibit C5a signalling, whereby the pro- inflammatory signal is inhibited. Based on the role of C5a and its receptor in stimulation of inflammation the invention further relates to therapeutic use of said human anti-C5aR antibodies and in particular in relation to treatment of immunological disorders.