ZAHN, STEFAN,ZEUTHEN, LOUISE HJERRILD,HANSEN, ANKER JON,KJÆRGAARD, KRISTIAN,LUND, SØREN
申请号:
PL12725447
公开号:
PL2718322T3
申请日:
2012.06.04
申请国别(地区):
PL
年份:
2019
代理人:
摘要:
The present invention concerns human antibodies recognizing the human C5a receptor. By binding to C5aR the antibodies inhibit C5a signaling, whereby the pro- inflammatory signal is inhibited. Based on the role of C5a and its receptor in stimulation of inflammation the invention further relates to therapeutic use of said human anti-C5aR antibodies and in particular in relation to treatment of immunological disorders.