ЭЙДЕЛМАН Дэниел С. (US),СИЛВЕРМАН Джеффри А. (US),АРКИН Майкл (US),ХАЙД Дженнифер (US),УОЛКЕР Дункан (US),РАЙТ Жасмин (US)
申请号:
RU2016124135
公开号:
RU2016124135A
申请日:
2016.06.17
申请国别(地区):
RU
年份:
2017
代理人:
摘要:
Methods of treating, preventing or managing cancer, including certain leukernias are disclosed. The methods encompass the administration of enantiomerically pure (+)-l,4- dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-l-pyrrolidinyl]-4-oxo-l-(2-thiazolyl)-l,8- naphthyridine-3-carboxylic acid. Also provided are methods of treatment using this compound with chemotherapy, radiation therapy, hormonal therapy, biological therapy or immunotherapy. Pharmaceutical compositions and single unit dosage forms suitable for use in the methods are also disclosed.