Methods of using (+)-1,4-dihydro-7-((3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl)-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer
Silverman, Jeffrey A.,Wright, Jasmin,Hyde, Jennifer,Adelman, Daniel C.,Arkin, Michael,Walker, Duncan
申请号:
AU2006287149
公开号:
AU2006287149B2
申请日:
2006.09.05
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
Methods of treating, preventing or managing cancer, including certain leukernias are disclosed. The methods encompass the administration of enantiomerically pure (+)-l,4- dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-l-pyrrolidinyl]-4-oxo-l-(2-thiazolyl)-l,8- naphthyridine-3-carboxylic acid. Also provided are methods of treatment using this compound with chemotherapy, radiation therapy, hormonal therapy, biological therapy or immunotherapy. Pharmaceutical compositions and single unit dosage forms suitable for use in the methods are also disclosed.